Guidelines for Proper NSAID Use


You could grab an OTC medication when you have a headache or muscle discomfort. The most popular option is a non-steroidal anti-inflammatory medication (NSAID). Yet even though you can buy drugs without a prescription, that does not mean they do not represent a risk. The following information will help you use them safely.


Non-steroidal anti-inflammatory medication refers to as NSAID. A type of medication- NSAID alleviates pain and inflammation. These can lower fever as well. These are available over-the-counter equivalents at lower doses.

For chronic illnesses including rheumatoid arthritis and osteoarthritis, higher doses may be recommendable. Before using OTC NSAIDs, see your physician if you are currently taking any of the following medications:

  • Diuretics, or “water pills”: NSAIDs can lessen the effects of diuretics because of how they affect the kidneys.
  • Methotrexate or lithium: As the kidneys are responsible for removing these drugs, a buildup could occur and raise the risk of side effects.
  • Blood pressure medications: When taken with NSAIDs, particularly when taken often, their effects may be diminished.
  • Aspirin: NSAIDs may lessen their effectiveness if taken in order to avoid a heart attack or stroke.
  • Blood thinners: Warfarin, for example, can raise the chance of bleeding
  • SSRI antidepressant medications: Sertraline (Zoloft) and fluoxetine (Prozac) are two examples of medications that can raise your risk of gastrointestinal and other types of bleeding.

How Does NSAID Function?

NSAIDs prevent the body from using COX-1 and COX-2 enzymes. These enzymes produce prostaglandins. In the body, there is a group of fatty acids like this. These fatty acids are very important in inflammation and discomfort.

What Are NSAIDs’ Typical Adverse Effects?

If you take NSAIDs often or in high amounts, you may experience side effects. When compared to more serious side effects that necessitate medical treatment, some side effects are minor and quickly go away. Do not take more than the recommended dose of an NSAID, several over-the-counter NSAIDs, or an NSAID with a prescription NSAID unless your doctor instructs you to. You might experience more negative effects if you do this.

The most frequent adverse effects are those listed below, although there could be others. If you have any queries concerning the specific drug you are taking, ask your doctor. The gastrointestinal (stomach and gut) side effects of NSAIDs are most frequently reported and include:

  • Gas.
  • Experiencing bloat.
  • Heartburn.
  • Stomach ache.
  • Nausea.
  • Vomiting.
  • Either constipation or diarrhea.

What Safeguards Can You Take While Taking NSAIDs?

NSAIDs sold over the counter are generally safe to use to treat minor aches and pains. Yet, you still need to use them wisely. To reduce any negative impacts or health hazards, remember to:

  • Consult a pharmacist or member of your healthcare team first
  • All of the prescription and over-the-counter medications you use should be disclosed to him or her. If an NSAID is unsafe for you, he or she can let you know. NSAIDs and some medications may interact. They include prescription drugs for high blood pressure and depression.
  • Observe your dosages and time
  • Take it only as directed and for as little time as necessary. Health issues may be more prevalent with higher doses. If you take the medication for ten days or longer, let your doctor know.
  • Review all medication labels
  • Take no more than two over-the-counter medications with the same active component. An overdose or negative effects are more likely to occur. Before taking more than one over-the-counter drug, read the Drug Information label. Be aware that some NSAIDs are present in cough and cold medications.
  • If you take aspirin regularly, avoid taking NSAIDs. NSAIDs can counteract aspirin’s beneficial benefits.
  • Also, look for warning indicators of issues
  • They include rashes, high blood pressure, heart difficulties, kidney problems, stomach troubles, and kidney problems.


Take the least amount necessary to treat your condition, and only take it for as long as necessary or as your physician recommends. To lessen some of the gastrointestinal adverse effects, take NSAIDs with food or milk. Also, to lower bleeding risks while using NSAIDs, avoid consuming alcohol. Moreover, always see your pharmacist or physician if you have any concerns about the dangers of using NSAIDs or if you have any other questions about these or any other medicines.